… synaptic plasticity and cell structure, neuroinflammation, impaired protein folding … Redox
proteomics analysis of carbonylated proteins in the hippocampus of 3-month-old 3xTg-AD mice …

… cognitive impairment and dementia coincident with progressive damage to brain neuronal
… include the development of extracellular amyloid plaques in the brain and the formation of …

… , partially improved clearance of amyloid β peptide only in the … in neuronal cell bodies and
plasma membrane where it co-… tau levels in the hippocampus of 3xTg-AD mice 4 months after …

… Ca 2+ in cortical neurons of 3xTg-AD animals was 247 nmol/… concentration transients near
the plasma membrane, both in … , two brain functions that are largely impaired in AD, by CaM. …

… The pathological convergence of tau and amyloid β-peptide (… of the cerebral cortices of
3XTg-AD mice occurred well … , VDAC has been found on the plasma membrane (plVDAC) of cells. …

… impairment. However, melatonin treatment attenuated … regions including the cerebral cortex
and hippocampus which … that Al treated mice showed no impairment in spatial learning and …

… plaques that are rich in amyloid β-peptide (Aβ), intraneuronal … protein that resides in the
plasma membrane. APP can be cleaved … Patients with AD and 3xTgAD mouse models show low …

… on both the amyloid-β peptide and surrounding molecules … display cognitive impairment
and hippocampal degeneration … and reduced amyloid-β and tau pathology in 3xTg AD mice […

… of AD, 216 cases of mild cognitive impairment, and 864 healthy controls … This cleavage occurs
at the plasma membrane and is … The 3xTG-AD, APP-PS1ΔE9, and APPswe/PS1ΔE9 mice …

… neurotoxic effects that impair the blood–brain barrier (BBB). … Amyloid-β peptide fragments
vary in length from around 36 to … a variety of cell lines, including mouse Lewis lung carcinoma …